What Parkinson's, ALS, and MS have in common

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As we have observed for several years, now researchers are catching up! Scientists are quickly discovering that gut microbiomes may hold the key to a vast amount of health issues including Parkinson's, ALS, MS and even Autism.

Researchers at the Weizman Institute of Science in Israel have demonstrated in mice that intestinal microbes, collectively known as the gut microbiome may affect the course of ALS, amyotrophic lateral sclerosis. As reported recently in the journal Nature, progressive of an ALS like disease was slowed after mice received specific strains of gut microbes or substances known to be secreted by and the preliminary findings suggest that these findings are likely applicable to humans as well.

The researchers, while far from declaring a cure for the diseases are optimistic that various means of altering the microbiome may be harnessed for developing new therapeutic options for ALS.

According to other recent research at the institute, gut bacteria abnormalities play a role in motor neurone diseases according to early studies in animals and people. The research team at the Weizman Institute says its studies suggest that the microbiome alters the brain in MS, autism and Parkinson's disease. These illnesses are a group of diseases that stop messages from the brain and spinal cord from reaching the muscles.

Following successful interventions in mice, the group has published their research in prestigious jou
als but are cautious not to imply that they have stopped, cured or reversed the diseases. There is some early stage work in people as well. Results showed that differences were found in the microbiomes and nicotinamide in the body suggesting a different metabolism for those people suffering from these illnesses. More research is planned.

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